PD 404182

Research use only, not for human use.

PD 404182 (PD404182, PD-404182) is a heterocyclic iminobenzothiazine derivative with antimicrobial and anti-inflammatory properties, a potent inhibitor of human DDAH1 activity (IC50=9 uM) and elevates cellular ADMA levels.

PD 404182 (PD404182, PD-404182) is a heterocyclic iminobenzothiazine derivative with antimicrobial and anti-inflammatory properties, a potent inhibitor of human DDAH1 activity (IC50=9 uM) and elevates cellular ADMA levels; significantly increases intracellular levels of ADMA and reduces LPS-induced NO production in cultured primary human vascular endothelial cells (ECs), abrogates the formation of tube-like structures by ECs in in vitro angiogenesis assay; also shows anti-HIV and anti-HSV activites.Bacterial Infection Discontinued

PD404182;PD-404182

Microbiology/Virology

HIV

HIV

Infection

Bacterial Infection

72596-74-8

217.29

C11H11N3S

>98% (HPLC)

——

N=C1SC2=CC=CC=C2C3=NCCCN13

6H-6-imino-(2,3,4,5-tetrahydropyrimido)[1,2-c]-[1,3]benzothiazine

(-20℃)

With Ice Pack

≥ 2 years